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If the precipitate the white deposit at the bottom of the vial has become lumpy or granular in appearance or has formed a deposit of solid particles on the wall of the vial, do not use it, and call Novo Nordisk at This insulin should not be used if the liquid in the vial remains clear after the vial has been gently rotated.

Read the instructions for use that come with your Novolin N product. Talk to your healthcare provider if you have any questions. Your healthcare provider should show you how to inject Novolin N before you start taking it.

See the end of this patient information for instructions about preparing and giving the injection. Severe low blood sugar hypoglycemia can cause unconsciousness passing out , seizures, and death.

Know your symptoms of low blood sugar. Talk to your healthcare provider if low blood sugar is a problem for you.

These are not all of the possible side effects from Novolin N. Ask your healthcare provider or pharmacist for more information.

Call your doctor for medical advice about side effects. Novolin N is used for the treatment of diabetes only.

Medicines are sometimes prescribed for conditions that are not mentioned in the patient leaflet. Do not use Novolin N for a condition for which it was not prescribed.

Do not give Novolin N to other people, even if they have the same symptoms you have. It may harm them. This leaflet summarizes the most important information about Novolin N.

If you would like more information about Novolin N or diabetes, talk with your healthcare provider. For more information, call or visit www.

Before starting, gather all of the supplies that you will need to use for preparing and giving your insulin injection. Different insulins should be mixed only under instruction from a health care provider.

Do not mix Novolin N with any other type of insulin besides Regular human insulin. Novolin N should be mixed only when injections with syringes are used.

Novolin N can be mixed with Regular human insulin right before use. When you are mixing Novolin N insulin with Regular human insulin, always draw the Regular human clear insulin into the syringe first.

Your physician has explained that you have diabetes and that your treatment involves injections of insulin or insulin therapy combined with an oral antidiabetic medicine.

Insulin is normally produced by the pancreas, a gland that lies behind the stomach. Without insulin, glucose a simple sugar made from digested food is trapped in the bloodstream and cannot enter the cells of the body.

Each case of diabetes is different and requires direct and continued medical supervision. Your physician has told you the type, strength and amount of insulin you should use and the time s at which you should inject it, and has also discussed with you a diet and exercise schedule.

You should contact your physician if you experience any difficulties or if you have questions. Standard and purified animal insulins as well as human insulins are available.

Standard and purified insulins differ in their degree of purification and content of noninsulin material. Standard and purified insulins also vary in species source; they may be of beef, pork, or mixed beef and pork origin.

Human insulin is identical in structure to the insulin produced by the human pancreas, and thus differs from animal insulins.

Your physician has prescribed the insulin that is right for you; be sure you have purchased the correct insulin and check it carefully before you use it.

The concentration of this product is units of insulin per milliliter. It is a cloudy or milky suspension of human insulin with protamine and zinc.

Novolin N has an intermediate duration of action. The effect is maximal between 4 and 12 hours. The full duration of action may last up to 24 hours after injection.

The time course of action of any insulin may vary considerably in different individuals, or at different times in the same individual. Because of this variation, the time periods listed here should be considered as general guidance only.

This human insulin recombinant DNA origin is structurally identical to the insulin produced by the human pancreas.

Do not let it freeze. Keep Novolin N PenFill cartridge in the carton so that they will stay clean and protected from light.

Unrefrigerated Novolin N PenFill cartridges must be discarded 14 days after the first use, even if they still contain Novolin N insulin.

Never use PenFill cartridges after the expiration date which is printed on the label and carton. Never use any Novolin N PenFill cartridge if the precipitate the white deposit has become lumpy or granular in appearance or has formed a deposit of solid particles on the wall of the cartridge.

This insulin should not be used if the liquid in the cartridge remains clear after it has been mixed. Failure to follow the antiseptic measures listed below may lead to infections at the injection site.

Never place a single-use disposable needle on your insulin delivery device until you are ready to give an injection, and remove it immediately after the injection.

If the needle is not removed, some liquid may be expelled from the cartridge causing a change in the insulin concentration strength.

The cloudy material in an insulin suspension will settle to the bottom of the cartridge, so the contents must be mixed before injection.

These Novolin PenFill cartridges contain a glass ball to aid mixing. When using a new cartridge, turn the cartridge up and down between positions A and B - See Figure 1.

Do this at least 10 times until the liquid appears uniformly white and cloudy. For subsequent injections when a cartridge is already in the device, turn the device up and down between positions A and B - See Figure 2.

Follow the directions in your insulin delivery device instruction manual. Note: Never initiate a new injection unless there is sufficient insulin in the cartridge to ensure proper mixing the glass ball needs adequate room for movement to mix the suspension.

PenFill cartridges may contain a small amount of air bubbles. To prevent an injection of air and to make certain a full dose of insulin is injected, an air shot must be done before each injection.

Directions for performing an air shot are provided in your delivery device instruction manual. The following areas are suitable for subcutaneous insulin injection: thighs, upper arms, buttocks, abdomen.

Do not change areas without consulting your physician. The actual point of injection should be changed each time; injection sites should be about an inch apart.

The injection site should be clean and dry. Pinch up skin area to be injected and hold it firmly. Hold the device like a pencil and push the needle quickly and firmly into the pinched-up area.

Release the skin and push the push button all the way in to inject insulin beneath the skin. After the injection, the needle should remain under the skin for at least 6 seconds.

Keep the push button fully depressed until the needle is withdrawn from the skin. This will ensure that the full dose has been injected. Do not inject into a muscle unless your physician has advised it.

You should never inject insulin into a vein. Follow the directions for use of your insulin delivery device. Remove the needle. If slight bleeding occurs, press lightly with a dry cotton swab for a few seconds - do not rub.

It is particularly important to maintain good control of your diabetes during pregnancy and special attention must be paid to your diet, exercise and insulin regimens.

If you are pregnant or nursing a baby, consult your physician or nurse educator. Insulin reaction hypoglycemia occurs when the blood glucose falls very low.

This can happen if you take too much insulin, miss or delay a meal, exercise more than usual, or work too hard without eating, or become ill especially with vomiting or fever.

Hypoglycemia can also happen if you combine insulin therapy and other medications that lower blood glucose, such as oral antidiabetic agents or other prescription and over-the-counter drugs.

The first symptoms of an insulin reaction usually come on suddenly. They may include a cold sweat, fatigue, nervousness or shakiness, rapid heartbeat, or nausea.

Personality change or confusion may also occur. If you drink or eat something right away a glass of milk or orange juice, or several sugar candies , you can often stop the progression of symptoms.

If symptoms persist, call your physician - an insulin reaction can lead to unconsciousness. If a reaction results in loss of consciousness, emergency medical care should be obtained immediately.

If you have had repeated reactions or if an insulin reaction has led to a loss of consciousness, contact your physician.

Severe hypoglycemia can result in temporary or permanent impairment of brain function and death. In certain cases, the nature and intensity of the warning symptoms of hypoglycemia may change.

A few patients have reported that after being transferred to human insulin, the early warning symptoms of hypoglycemia were less pronounced than they had been with animal-source insulin.

Diabetic ketoacidosis may develop if your body has too little insulin. The most common causes are acute illness or infection or failure to take enough insulin by injection.

If you are ill, you should check your urine for ketones. Man kann Novoline kostenlos spielen, ohne Anmeldung, deutsch oder englisch, ganz wie man gerade möchte.

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Categories : Disambiguation pages. Hidden categories: Disambiguation pages with short descriptions Short description is different from Wikidata All article disambiguation pages All disambiguation pages.

Namespaces Article Talk. Views Read Edit View history. Help Community portal Recent changes Upload file. Download as PDF Printable version.

Add links. These are not all of the possible side effects from Novolin N. Ask your healthcare provider or pharmacist for more information.

Call your doctor for medical advice about side effects. Novolin N is used for the treatment of diabetes only.

Medicines are sometimes prescribed for conditions that are not mentioned in the patient leaflet. Do not use Novolin N for a condition for which it was not prescribed.

Do not give Novolin N to other people, even if they have the same symptoms you have. It may harm them. This leaflet summarizes the most important information about Novolin N.

If you would like more information about Novolin N or diabetes, talk with your healthcare provider.

For more information, call or visit www. Before starting, gather all of the supplies that you will need to use for preparing and giving your insulin injection.

Different insulins should be mixed only under instruction from a health care provider. Do not mix Novolin N with any other type of insulin besides Regular human insulin.

Novolin N should be mixed only when injections with syringes are used. Novolin N can be mixed with Regular human insulin right before use. When you are mixing Novolin N insulin with Regular human insulin, always draw the Regular human clear insulin into the syringe first.

Your physician has explained that you have diabetes and that your treatment involves injections of insulin or insulin therapy combined with an oral antidiabetic medicine.

Insulin is normally produced by the pancreas, a gland that lies behind the stomach. Without insulin, glucose a simple sugar made from digested food is trapped in the bloodstream and cannot enter the cells of the body.

Each case of diabetes is different and requires direct and continued medical supervision. Your physician has told you the type, strength and amount of insulin you should use and the time s at which you should inject it, and has also discussed with you a diet and exercise schedule.

You should contact your physician if you experience any difficulties or if you have questions. Standard and purified animal insulins as well as human insulins are available.

Standard and purified insulins differ in their degree of purification and content of noninsulin material. Standard and purified insulins also vary in species source; they may be of beef, pork, or mixed beef and pork origin.

Human insulin is identical in structure to the insulin produced by the human pancreas, and thus differs from animal insulins.

Your physician has prescribed the insulin that is right for you; be sure you have purchased the correct insulin and check it carefully before you use it.

The concentration of this product is units of insulin per milliliter. It is a cloudy or milky suspension of human insulin with protamine and zinc. Novolin N has an intermediate duration of action.

The effect is maximal between 4 and 12 hours. The full duration of action may last up to 24 hours after injection. The time course of action of any insulin may vary considerably in different individuals, or at different times in the same individual.

Because of this variation, the time periods listed here should be considered as general guidance only. This human insulin recombinant DNA origin is structurally identical to the insulin produced by the human pancreas.

Do not let it freeze. Keep Novolin N PenFill cartridge in the carton so that they will stay clean and protected from light.

Unrefrigerated Novolin N PenFill cartridges must be discarded 14 days after the first use, even if they still contain Novolin N insulin.

Never use PenFill cartridges after the expiration date which is printed on the label and carton. Never use any Novolin N PenFill cartridge if the precipitate the white deposit has become lumpy or granular in appearance or has formed a deposit of solid particles on the wall of the cartridge.

This insulin should not be used if the liquid in the cartridge remains clear after it has been mixed. Failure to follow the antiseptic measures listed below may lead to infections at the injection site.

Never place a single-use disposable needle on your insulin delivery device until you are ready to give an injection, and remove it immediately after the injection.

If the needle is not removed, some liquid may be expelled from the cartridge causing a change in the insulin concentration strength.

The cloudy material in an insulin suspension will settle to the bottom of the cartridge, so the contents must be mixed before injection.

These Novolin PenFill cartridges contain a glass ball to aid mixing. When using a new cartridge, turn the cartridge up and down between positions A and B - See Figure 1.

Do this at least 10 times until the liquid appears uniformly white and cloudy. For subsequent injections when a cartridge is already in the device, turn the device up and down between positions A and B - See Figure 2.

Follow the directions in your insulin delivery device instruction manual. Note: Never initiate a new injection unless there is sufficient insulin in the cartridge to ensure proper mixing the glass ball needs adequate room for movement to mix the suspension.

PenFill cartridges may contain a small amount of air bubbles. To prevent an injection of air and to make certain a full dose of insulin is injected, an air shot must be done before each injection.

Directions for performing an air shot are provided in your delivery device instruction manual. The following areas are suitable for subcutaneous insulin injection: thighs, upper arms, buttocks, abdomen.

Do not change areas without consulting your physician. The actual point of injection should be changed each time; injection sites should be about an inch apart.

The injection site should be clean and dry. Pinch up skin area to be injected and hold it firmly. Hold the device like a pencil and push the needle quickly and firmly into the pinched-up area.

Release the skin and push the push button all the way in to inject insulin beneath the skin. After the injection, the needle should remain under the skin for at least 6 seconds.

Keep the push button fully depressed until the needle is withdrawn from the skin. This will ensure that the full dose has been injected.

Do not inject into a muscle unless your physician has advised it. You should never inject insulin into a vein. Follow the directions for use of your insulin delivery device.

Remove the needle. If slight bleeding occurs, press lightly with a dry cotton swab for a few seconds - do not rub. It is particularly important to maintain good control of your diabetes during pregnancy and special attention must be paid to your diet, exercise and insulin regimens.

If you are pregnant or nursing a baby, consult your physician or nurse educator. Insulin reaction hypoglycemia occurs when the blood glucose falls very low.

This can happen if you take too much insulin, miss or delay a meal, exercise more than usual, or work too hard without eating, or become ill especially with vomiting or fever.

Hypoglycemia can also happen if you combine insulin therapy and other medications that lower blood glucose, such as oral antidiabetic agents or other prescription and over-the-counter drugs.

The first symptoms of an insulin reaction usually come on suddenly. They may include a cold sweat, fatigue, nervousness or shakiness, rapid heartbeat, or nausea.

Personality change or confusion may also occur. If you drink or eat something right away a glass of milk or orange juice, or several sugar candies , you can often stop the progression of symptoms.

If symptoms persist, call your physician - an insulin reaction can lead to unconsciousness. If a reaction results in loss of consciousness, emergency medical care should be obtained immediately.

If you have had repeated reactions or if an insulin reaction has led to a loss of consciousness, contact your physician.

Severe hypoglycemia can result in temporary or permanent impairment of brain function and death. In certain cases, the nature and intensity of the warning symptoms of hypoglycemia may change.

A few patients have reported that after being transferred to human insulin, the early warning symptoms of hypoglycemia were less pronounced than they had been with animal-source insulin.

Diabetic ketoacidosis may develop if your body has too little insulin. The most common causes are acute illness or infection or failure to take enough insulin by injection.

If you are ill, you should check your urine for ketones. The symptoms of diabetic ketoacidosis usually come on gradually, over a period of hours or days, and include a drowsy feeling, flushed face, thirst and loss of appetite.

Notify your physician right away if the urine test is positive for ketones acetone or if you have any of these symptoms.

Fast, heavy breathing and rapid pulse are more severe symptoms and you should have medical attention right away.

Severe, sustained hyperglycemia may result in diabetic coma and death. A few people with diabetes develop red, swollen and itchy skin where the insulin has been injected.

Generalized insulin allergy occurs rarely, but when it does it may cause a serious reaction, including skin rash over the body, shortness of breath, fast pulse, sweating, and a drop in blood pressure.

If any of these symptoms develop, you should seek emergency medical care. If severe allergic reactions to insulin have occurred i.

A change in the type, strength, species or purity of insulin could require a dosage adjustment.

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